Jean-Loup Faulon

Work and research

"Our group is interested in systems metabolic engineering and synthetic biology. We develop in silico and experimental methods to search and design chemical and biological networks constrained by experimental data. The applications of our work include metabolic pathway design, construction and characterization. Other activities include structure-activity relationships, and rational molecular design."

  • Teaching (ISSB - Master 2 in Systems and synthetic biology)


  • Publications

  1. Carbonell, P., Parutto, P., Baudier, C., Junot, C., Faulon, J.L. Retropath: automated pipeline for embedded metabolic circuits. ACS Synthetic Biology, accepted, 2013. (link to journal)
  2. Carbonell, P., Carlsson, L., Faulon, J.L. Stereo signature molecular descriptor. J Chem Inf Model, 53(4): 887-897, 2013. (link to journal)
  3. Joo, J., Plimpton, S.J., Faulon, J.L. Statistical Ensemble Analysis for Simulating Extrinsic Noise-driven Response in NF-kappaB Signaling Network. BMC Systems Biology, accepted, 2013
  4. Pauthenier, C., Carbonell, P., Faulon, J.L. La conception rationnelle de ferments biologiques : comment concevoir un micro-organisme pour produire un composé chimique spécifique. L'Actualité Chimique, 375: 30-36, 2013.
  5. Carbonell, P., Planson, A.G., Faulon, J.L. Retrosynthetic design of heterologous pathways. Methods in Molecular Biology, 2013,985:149-73. (link to journal)
  6. Planson, A.G., Carbonell, P., Grigoras, I., Faulon, J.L. A retrosynthetic biology approach to therapeutics: from conception to delivery. Current Opinion in Biotechnology, 2012, 23:948-956. (link to journal)
  7. Carbonell, P., Fichera, D., Pandit, S.B., Faulon, J.L. Enumerating metabolic pathways for the production of heterologous target chemicals in chassis organisms. BMC Systems Biology, 2012, 6:10. (link to journal)
  8. Planson A.G., Carbonell P., Paillard E., Pollet N., Faulon J.L. Compound toxicity screening and structure-activity relationship modeling in Escherichia coli. Biotechnology and Bioengineering, 2012, 109(3):846-850. (link to journal)
  9. Peironcely J.E., Rojas-Chertó M., Fichera D., Reijmers T., Coulier L., Faulon J.L., Hankemeier, T. OMG: open molecule generator. J. Cheminf , 2012, 4:21 . (link to journal)
  10. Misra M. , Martin S., Faulon J.L. Graphs: Flexible Representations of Molecular Structures and Biological Networks, in Computational Approaches in Cheminformatics and Bioinformatics, Guha R., Bender, A. Edts, Wiley, 2012. (link to journal)


Biology Department
Evry University, UniverSud Paris
ISSB, Genopole®
Genopole Campus 1, Genavenir 6
5, rue Henri Desbruères
91030 Evry cedex, France

+33 (0)1 69 47 44 47
+33 (0)1 69 47 44 37

Administrative assistant : +33 (0)1 69 47 44 30